Claudin 4 anticorps (AA 21-120)

N° du produit ABIN680743

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 4 dans WB, ELISA, IF (cc), IF (p) et IHC (fro). Il présente une réactivité envers Humain et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour Claudin 4 anticorps (AA 21-120) (ABIN680743)

Antigène: Claudin 4 (CLDN4)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Claudin 4 anticorps

Épitope: AA 21-120

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CLDN4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Claudin 4 (ABIN680743)

Wang, Chen, Liang, Yan, Lin, Liu, Luo, Huang, Li, Liu, Tang: "Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?." dans: Cell and tissue research, Vol. 357, Issue 1, pp. 173-84, (2014) (PubMed).

Détails sur Claudin 4

Antigène: Claudin 4 (CLDN4)

Autre désignation: Claudin 4

Sujet:

Synonyms: CPER, CPE-R, CPETR, CPETR1, WBSCR8, hCPE-R, Claudin-4, Clostridium perfringens enterotoxin receptor, CPE-receptor, Williams-Beuren syndrome chromosomal region 8 protein, CLDN4

Background: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

ID gène: 1364

UniProt: O14493

Pathways: Hepatitis C