ASB2 anticorps (AA 501-587) (HRP)

N° du produit ABIN681097

Cet anticorps Lapin Polyclonal détecte spécifiquement ASB2 dans ELISA, WB, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour ASB2 anticorps (AA 501-587) (HRP) (ABIN681097)

Antigène: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASB2 est conjugé à/à la HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ASB2 anticorps (HRP)

Épitope: AA 501-587

Homologie: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ASB2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ASB2

Antigène: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Autre désignation: ASB2

Sujet:

Synonyms: Ankyrin repeat and SOCS box 2 containing protein, Ankyrin repeat and SOCS box containing 2, Ankyrin repeat and SOCS box containing protein 2, Ankyrin repeat containing protein ASB2.ASB2_HUMAN

Background: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

ID gène: 51676