LPAR1 anticorps (AA 281-364)

N° du produit ABIN681103

Cet anticorps Lapin Polyclonal détecte spécifiquement LPAR1 dans WB, ELISA, IF (p) et IHC (p). Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour LPAR1 anticorps (AA 281-364) (ABIN681103)

Antigène: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LPAR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LPAR1 anticorps

Épitope: AA 281-364

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EDG2/LPAR1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-LPAR1 (ABIN681103)

Chen, Zhang, Deng, Liu, Yang, Wu, Yu: "Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI." dans: Biochemical and biophysical research communications, Vol. 491, Issue 3, pp. 587-594, (2017) (PubMed).

Détails sur LPAR1

Antigène: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Autre désignation: LPAR1

Sujet:

Synonyms: EDG2, LPA1, VZG1, GPR26, edg-2, vzg-1, Gpcr26, Mrec1.3, rec.1.3, Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2, LPAR1

Background: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.

ID gène: 1902

UniProt: Q92633

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration