HDAC8 anticorps (AA 151-250)

N° du produit ABIN681268

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC8 dans IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour HDAC8 anticorps (AA 151-250) (ABIN681268)

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC8 est non-conjugé

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HDAC8 anticorps

Épitope: AA 151-250

Fonction: HDAC8 Polyclonal Antibody

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HDAC8

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HDAC8

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Autre désignation: HDAC8

Sujet:

Synonyms: HD8, WTS, RPD3, CDA07, CDLS5, MRXS6, HDACL1, Histone deacetylase 8, HDAC8

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

ID gène: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process