OXSR1 anticorps (AA 201-300)
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- Antigène Voir toutes OXSR1 Anticorps
- OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))
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Épitope
- AA 201-300
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp OXSR1 est non-conjugé
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human OXSR1.
- Isotype
- IgG
- Top Product
- Discover our top product OXSR1 Anticorps primaire
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))
- Autre désignation
- OXSR1 (OXSR1 Produits)
- Synonymes
- anticorps OSR1, anticorps C20orf111, anticorps HSPC207, anticorps Osr1, anticorps Perit1, anticorps dJ1183I21.1, anticorps zgc:55494, anticorps zgc:77321, anticorps OXSR1, anticorps 2210022N24Rik, anticorps 2810422B09Rik, anticorps AI462649, anticorps AW209236, anticorps mKIAA1101, anticorps odd1, anticorps osr1, anticorps wu:fb77f12, anticorps zgc:165661, anticorps oxidative stress responsive 1, anticorps oxidative stress responsive serine rich 1, anticorps oxidative stress responsive 1b, anticorps serine/threonine-protein kinase OSR1, anticorps odd-skipped related transciption factor 1, anticorps oxidative-stress responsive 1, anticorps oxidative stress responsive 1a, anticorps OXSR1, anticorps OSER1, anticorps oxsr1b, anticorps CpipJ_CPIJ015177, anticorps Tsp_00299, anticorps OSR1, anticorps Oxsr1, anticorps LOC106505565, anticorps oxsr1, anticorps oxsr1a
- Sujet
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Synonyms: KIAA1101, OSR 1, OSR1, Oxidative stress responsive 1, Oxidative stress responsive 1 protein, OXSR 1, Serine/threonine protein kinase OSR1.
Background: OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
- ID gène
- 9943
- Pathways
- Tube Formation
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