Acetyl-CoA Carboxylase anticorps (pSer78)
Aperçu rapide pour Acetyl-CoA Carboxylase anticorps (pSer78) (ABIN683203)
Antigène
Voir toutes Acetyl-CoA Carboxylase AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer78
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A carboxylase alpha around the phosphorylation site of Ser78
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Isotype
- IgG
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Indications d'application
- IHC-P (1:100-500),IF (p) (1:100-500)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- Acetyl-CoA Carboxylase
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Autre désignation
- Acetyl CoA Carboxylase
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Sujet
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Synonyms: Acetyl Coenzyme A Carboxylase alpha phospho S78, p-Acetyl Coenzyme A Carboxylase alpha phospho S78, ACAC, ACACA, ACACA, ACACA_HUMAN, ACC alpha, ACC, ACC-alpha, ACC1, ACC1, ACCA, acetyl CoA carboxylase 1, acetyl Coenzyme A, Acetyl Coenzyme A, Biotin carboxylase, Acetyl-Coenzyme A Carboxylase alpha.
Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Poids moléculaire
- 266kDa
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ID gène
- 32
Antigène
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