Acetyl-CoA Carboxylase anticorps (pSer78)

N° du produit ABIN683203

Détail du produit anti-Acetyl-CoA Carboxylase anticorps

Antigène: Acetyl-CoA Carboxylase

Épitope: pSer78

Reactivité: Humain, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase est non-conjugé

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A carboxylase alpha around the phosphorylation site of Ser78

Isotype: IgG

Information d'application

Indications d'application: IHC-P (1:100-500),IF (p) (1:100-500)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Acetyl-CoA Carboxylase

Antigène: Acetyl-CoA Carboxylase

Autre désignation: Acetyl CoA Carboxylase (Acetyl-CoA Carboxylase Produits)

Synonymes: anticorps ACAC, anticorps acetyl-CoA carboxylase alpha, anticorps ACACA

Sujet:

Synonyms: Acetyl Coenzyme A Carboxylase alpha phospho S78, p-Acetyl Coenzyme A Carboxylase alpha phospho S78, ACAC, ACACA, ACACA, ACACA_HUMAN, ACC alpha, ACC, ACC-alpha, ACC1, ACC1, ACCA, acetyl CoA carboxylase 1, acetyl Coenzyme A, Acetyl Coenzyme A, Biotin carboxylase, Acetyl-Coenzyme A Carboxylase alpha.

Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Poids moléculaire: 266kDa

ID gène: 32