DOK2 anticorps (pTyr351)

N° du produit ABIN684148

Cet anticorps Lapin Polyclonal détecte spécifiquement DOK2 dans WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour DOK2 anticorps (pTyr351) (ABIN684148)

Antigène: DOK2

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DOK2 anticorps

Épitope: pTyr351

Specificité: This phosphorylation site is found at Tyr345 in Human. Due to the highly conserved nature of this sequence with DOK1, this antibody may react with DOK1 when it is phosphorylated at Tyr362 in Human and Tyr361 in Mouse and Rat.

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from mouse p56Dok2 around the phosphorylation site of (Tyr351)

Isotype: IgG

Information d'application

Indications d'application: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DOK2

Antigène: DOK2

Autre désignation: Dok2

Sujet:

Synonyms: DokR, Frip, Docking protein 2, Dok-related protein, Dok-R, Downstream of tyrosine kinase 2, IL-four receptor-interacting protein, p56(dok-2), Dok2

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.

ID gène: 13449

UniProt: O70469