ARFIP2 anticorps (AA 221-341) (Biotin)

N° du produit ABIN686589

Cet anticorps anti-ARFIP2 est un anticorps Lapin Polyclonal détectant ARFIP2 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Humain.

Aperçu rapide pour ARFIP2 anticorps (AA 221-341) (Biotin) (ABIN686589)

Antigène: ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARFIP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ARFIP2 anticorps (Biotin)

Épitope: AA 221-341

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Arfaptin 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ARFIP2

Antigène: ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))

Autre désignation: Arfaptin 2

Sujet:

Synonyms: ARFIP2, arfaptin 2, ADP-ribosylation factor interacting protein 2, Partner of RAC1, POR1, ARFP2_HUMAN .

Background: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

ID gène: 23647