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ARFIP2 anticorps (AA 221-341) (Biotin)

ARFIP2 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN686589
  • Antigène Voir toutes ARFIP2 Anticorps
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Épitope
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-341
    Reactivité
    • 31
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 2
    Lapin
    Clonalité
    • 30
    • 1
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ARFIP2 est conjugé à/à la Biotin
    Application
    • 27
    • 14
    • 14
    • 10
    • 4
    • 4
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Arfaptin 2
    Isotype
    IgG
    Top Product
    Discover our top product ARFIP2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Autre désignation
    Arfaptin 2 (ARFIP2 Produits)
    Synonymes
    anticorps POR1, anticorps 2310002N04Rik, anticorps POR, anticorps Por1, anticorps ARFIP2, anticorps im:7136059, anticorps zgc:112066, anticorps ADP ribosylation factor interacting protein 2, anticorps ADP-ribosylation factor interacting protein 2, anticorps ADP-ribosylation factor interacting protein 2b, anticorps ARFIP2, anticorps Arfip2, anticorps arfip2b
    Sujet

    Synonyms: ARFIP2, arfaptin 2, ADP-ribosylation factor interacting protein 2, Partner of RAC1, POR1, ARFP2_HUMAN .

    Background: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

    ID gène
    23647
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