TRAP1 anticorps (AA 501-650) (FITC)

N° du produit ABIN686654

L’anticorps Lapin Polyclonal anti-TRAP1 a été validé pour IF (cc) et IF (p). Il convient pour détecter TRAP1 dans des échantillons de Rat. Il y a 1 publication disponible.

Aperçu rapide pour TRAP1 anticorps (AA 501-650) (FITC) (ABIN686654)

Antigène: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAP1 est conjugé à/à la FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-TRAP1 anticorps (FITC)

Épitope: AA 501-650

Réactivité croisée: Rat

Homologie: Human,Mouse,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSP75

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TRAP1 (FITC) (ABIN686654)

Lettini, Sisinni, Condelli, Matassa, Simeon, Maddalena, Gemei, Lopes, Vita, Del Vecchio, Esposito, Landriscina: "TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." dans: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).

Détails sur TRAP1

Antigène: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Autre désignation: Hsp75/Trap1

Sujet:

Synonyms: HSP75, HSP 75, HSP90L, TRAP-1, Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP1

Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

ID gène: 10131

UniProt: Q12931