Cathepsin L anticorps (AA 71-170)

N° du produit ABIN687532

Cet anticorps Lapin Polyclonal détecte spécifiquement Cathepsin L dans WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité envers Humain, Rat et Porc et a été mentionné dans 1 publication.

Aperçu rapide pour Cathepsin L anticorps (AA 71-170) (ABIN687532)

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivité: Humain, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Cathepsin L anticorps

Épitope: AA 71-170

Réactivité croisée: Humain, Porc, Rat

Homologie: Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse capsin L1 proprotein

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Cathepsin L (ABIN687532)

Hernáez, Guerra, Salas, Andrés: "African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes." dans: PLoS pathogens, Vol. 12, Issue 4, pp. e1005595, (2016) (PubMed).

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: Cathepsin L

Sujet:

Synonyms: fs, MEP, nkt, Ctsl1, 1190035F06Rik, Cathepsin L1, Cathepsin L, Major excreted protein, p39 cysteine proteinase, Ctsl

Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

ID gène: 13039

UniProt: P06797

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades