EpCAM anticorps (N-Term) (CF®488A)
Aperçu rapide pour EpCAM anticorps (N-Term) (CF®488A) (ABIN6934075)
Antigène
Voir toutes EpCAM (EPCAM) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 20-60, N-Term
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Specificité
- Recognizes a 40-43 kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
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Aucune reactivité croisée
- Souris, Rat (Rattus)
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Purification
- Purified by Protein A/G
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Immunogène
- A synthetic peptide (around aa 20-60) from the N-terminus of human TACSTD1 protein
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Isotype
- IgG1 kappa
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Indications d'application
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Positive Control: HT29 or SK-OV-3 cells (FACS/IF). Breast carcinoma (IHC).
Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 100 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
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Autre désignation
- TACSTD1
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Poids moléculaire
- 40-43kDa
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ID gène
- 4072
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UniProt
- P16422
Antigène
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