alpha Fetoprotein anticorps

N° du produit ABIN6936365

Cet anticorps Souris Monoclonal détecte spécifiquement alpha Fetoprotein dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour alpha Fetoprotein anticorps (ABIN6936365)

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp alpha Fetoprotein est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: C3

Détail du produit anti-alpha Fetoprotein anticorps

Specificité: It recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Aucune reactivité croisée: Boeuf (Vache), Souris, Rat (Rattus)

Réactivité croisée (Details): Human. Monkey. Dog. Pig. Does not react with Cow, Mouse or Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Alpha feto protein (AFP) Purified from serum of a hepatoma patient

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Hep-G2 cells. Fetal liver or hepatocellular carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur alpha Fetoprotein

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Autre désignation: AFP

Sujet: Alpha fetoglobulin, FETA, HPAFP,AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker)
Cellular localisation: Cytoplasmic

Poids moléculaire: 70kDa

ID gène: 174, 518808

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process