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alpha Fetoprotein anticorps

Cet anticorps anti-alpha Fetoprotein est un anticorps Souris Monoclonal détectant alpha Fetoprotein dans IF et IHC (f). Adapté pour Humain.
N° du produit ABIN6936367

Aperçu rapide pour alpha Fetoprotein anticorps (ABIN6936367)

Antigène

Voir toutes alpha Fetoprotein (AFP) Anticorps
alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivité

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Humain

Hôte

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Souris

Clonalité

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Monoclonal

Conjugué

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Cet anticorp alpha Fetoprotein est non-conjugé

Application

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Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone

C2-C3-MBS-12
  • Specificité

    It recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant full-length human Alpha feto protein

    Isotype

    IgG1 kappa
  • Indications d'application

    Known_Application: Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2 cells. Fetal liver or hepatocellular carcinoma.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

    Autre désignation

    AFP

    Sujet

    Alpha fetoglobulin, FETA, HPAFP,AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker)
    Cellular localisation: Cytoplasmic

    Poids moléculaire

    70kDa

    ID gène

    174, 518808

    UniProt

    P02771

    Pathways

    C21-Steroid Hormone Metabolic Process
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