Liver Arginase anticorps (AA 11-97)

N° du produit ABIN6936429

L’anticorps Souris Monoclonal anti-Liver Arginase a été validé pour WB et IHC (f). Il convient pour détecter Liver Arginase dans des échantillons de Humain.

Aperçu rapide pour Liver Arginase anticorps (AA 11-97) (ABIN6936429)

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Liver Arginase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: ARG1-1125

Détail du produit anti-Liver Arginase anticorps

Épitope: AA 11-97

Specificité: Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Réactivité croisée (Details): Human. Others not known.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)

Isotype: IgG3 kappa

Information d'application

Indications d'application:

Known_Application: Western Blotting (1-2 μg/mL),Immunohistology (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: 293Tcells. Hepatocellular Carcinoma (HCC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: ARG1

Sujet: Arginase 1, ARG1, liver-type arginase, type I arginase,Arginase1 (Hepatocellular Carcinoma Marker)
Cellular localisation: Cytoplasmic

Poids moléculaire: 35-38kDa

ID gène: 383, 440934

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin