BTLA anticorps

N° du produit ABIN6936534

L’anticorps Souris Monoclonal anti-BTLA a été validé pour ELISA et Coat. Il convient pour détecter BTLA dans des échantillons de Humain.

Aperçu rapide pour BTLA anticorps (ABIN6936534)

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BTLA est non-conjugé

Application: ELISA, Coating (Coat)

Clone: BTLA-1528

Détail du produit anti-BTLA anticorps

Specificité: B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human BTLA protein

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: Human lymph node or MDAMB468 xenograft.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur BTLA

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Autre désignation: BTLA

Sujet: B and T lymphocyte associated protein, B and T lymphocyte attenuator, B and T lymphocyte associated, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, BTLA, BTLA_HUMAN, BTLA1, CD272, CD272 antigen, FLJ16065, MGC129743,BTLA
Cellular localisation: Membrane

Poids moléculaire: 33kDa

ID gène: 151888, 445162

Pathways: Cancer Immune Checkpoints