CD1b anticorps

N° du produit ABIN6936627

Détail du produit anti-CD1b anticorps

Antigène: CD1b (CD1B)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD1b est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Coating (Coat)

Specificité: The Mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human peripheral lymphocytes

Clone: RIV12

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: MOLT4 cells. Human thymus.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD1b

Antigène: CD1b (CD1B)

Autre désignation: CD1B (CD1B Produits)

Synonymes: anticorps CD1, anticorps CD1A, anticorps R1, anticorps CD1B3, anticorps CD1B, anticorps CD1-b, anticorps CD1b molecule, anticorps T-cell surface glycoprotein CD1b-3, anticorps CD1b1 molecule, anticorps T-cell surface glycoprotein CD1b1, anticorps CD1B, anticorps LOC443423, anticorps CD1B1, anticorps LOC100720602

Sujet: A1 domain, CD1B, Cortical thymocyte antigen CD1B, hTa1 thymocyte antigen, Ly38, T cell surface glycoprotein CD1b, T6/Leu6,CD1b (T-Cell Surface Glycoprotein)
Cellular localisation: Cell surface

Poids moléculaire: 49kDa

ID gène: 910, 1310

UniProt: P29016