CD2 anticorps

N° du produit ABIN6936633

L’anticorps anti-CD2 Monoclonal Souris est utilisé pour la détection de CD2 dans des échantillons de Humain, Porc, Singe, Babouin et Chimpanzé. Il a été validé pour FACS, IF et Func.

Aperçu rapide pour CD2 anticorps (ABIN6936633)

Antigène: CD2

Reactivité: Humain, Porc, Singe, Babouin, Chimpanzé

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: RPA-2-10

Détail du produit anti-CD2 anticorps

Fonction: CD2 / Lymphocyte Function Antigen 2 (LFA-2) Antibody

Specificité: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Réactivité croisée (Details): Human. Chimpanzee. Baboon. Monkey. Pig.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human CD2 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Functional Studies (Order Ab without Azide), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: 293T or Jurkat cells. Lymph node and tonsil.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD2

Antigène: CD2

Autre désignation: CD2

Sujet:

Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11

293T or Jurkat cells. Lymph node and tonsil.

Poids moléculaire: ~50kDa

ID gène: 914, 523500

UniProt: P06729