Recombinant CD207 anticorps (AA 74-213)

N° du produit ABIN6936636

L’anticorps Souris Monoclonal anti-CD207 a été validé pour WB, ELISA et Coat. Il convient pour détecter CD207 dans des échantillons de Humain.

Aperçu rapide pour Recombinant CD207 anticorps (AA 74-213) (ABIN6936636)

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat)

Clone: RLGRN-1821

Détail du produit anti-CD207 anticorps

Épitope: AA 74-213

Specificité: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or A549 cells (WB).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: CD207

Sujet: C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin,Langerin / CD207 (Marker of Langerhans Cells)
Cellular localisation: Cell surface and cytoplasmic

Poids moléculaire: 48kDa

ID gène: 50489, 199731

UniProt: Q9UJ71