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Recombinant CD207 anticorps (AA 74-213)

CD207 Reactivité: Humain WB, ELISA, Coat Hôte: Souris Monoclonal rLGRN-1821 unconjugated Recombinant Antibody
N° du produit ABIN6936636
  • Antigène Voir toutes CD207 Anticorps
    CD207 (CD207 Molecule, Langerin (CD207))
    Type d'anticorp
    Recombinant Antibody
    Épitope
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 74-213
    Reactivité
    • 46
    • 34
    • 20
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 16
    Souris
    Clonalité
    • 40
    • 16
    Monoclonal
    Conjugué
    • 29
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD207 est non-conjugé
    Application
    • 41
    • 18
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Coating (Coat)
    Specificité
    Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
    Clone
    RLGRN-1821
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD207 Anticorps primaire
  • Indications d'application

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or A549 cells (WB).

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    CD207 (CD207 Molecule, Langerin (CD207))
    Autre désignation
    CD207 (CD207 Produits)
    Synonymes
    anticorps CD207, anticorps CLEC4K, anticorps RGD1565913, anticorps CD207 molecule, anticorps CD207 antigen, anticorps CD207, anticorps Cd207
    Sujet
    C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin,Langerin / CD207 (Marker of Langerhans Cells)
    Cellular localisation: Cell surface and cytoplasmic
    Poids moléculaire
    48kDa
    ID gène
    50489, 199731
    UniProt
    Q9UJ71
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