CD27 anticorps

N° du produit ABIN6936647

Cet anticorps Souris Monoclonal détecte spécifiquement CD27 dans FACS et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD27 anticorps (ABIN6936647)

Antigène: CD27 (CD27 Molecule (CD27))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD27 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 203-6

Détail du produit anti-CD27 anticorps

Fonction: CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Antibody

Specificité: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogène: Sezary cells

Isotype: IgG3, kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: Human peripheral blood lymphocytes. Human tonsil and lymph node.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD27

Antigène: CD27 (CD27 Molecule (CD27))

Autre désignation: CD27

Sujet:

LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7

Human peripheral blood lymphocytes. Human tonsil and lymph node.

Poids moléculaire: 120kDa

ID gène: 939, 355307

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints