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CD6 anticorps

CD6 Reactivité: Humain FACS, IF, IHC (f) Hôte: Souris Monoclonal 3F7B5 unconjugated

N° du produit ABIN6936765

Fiche de données

Antigène Voir toutes CD6 Anticorps

CD6
Reactivité
83

29

21

1

1

1

1
Humain
Hôte
52

36

4
Souris
Anticorps secondaires appropriés
Clonalité
58

34
Monoclonal
Conjugué
38

8

7

7

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD6 est non-conjugé
Application
55

51

33

18

17

15

11

8

5

4

3

2

1
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Réactivité croisée (Details)

Human.

Purification

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène

Human rheumatoid synovial T cell line ST-1

Clone

3F7B5

Isotype

IgG1 kappa

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CD6 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-98 PE

Indications d'application

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MOLT-4, CCRF-CEM, Jurkat cells, Tonsil.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur

Azide free

Stock

-20 °C,-80 °C

Stockage commentaire

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption

24 months
Antigène

CD6

Autre désignation

CD6 (CD6 Produits)

Synonymes

anticorps TP120, anticorps OX52, anticorps CD6 antigen, anticorps CD6 molecule, anticorps Cd6 molecule, anticorps Cd6, anticorps CD6

Sujet

T12, TP120,CD6 (Negative Marker of T-regulatory Cells)
Cellular localisation: Cell surface and cytoplasmic

Poids moléculaire

90-130kDa

ID gène

923, 744366

UniProt

P30203