P-Cadherin anticorps

N° du produit ABIN6936895

Cet anticorps anti-P-Cadherin Monoclonal Souris (Clone 12H6) (ABIN6936895) détecte spécifiquement P-Cadherin dans WB, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour P-Cadherin anticorps (ABIN6936895)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 12H6

Détail du produit anti-P-Cadherin anticorps

Fonction: P-Cadherin (CDH3) Antibody

Specificité: Recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human P-cadherin fusion protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.

Positive_Control: A431 or PC-3 cells. Pancreas, Placenta or Prostate.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3

Sujet:

Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin

A431 or PC-3 cells. Pancreas, Placenta or Prostate.

Poids moléculaire: 116kDa

ID gène: 1001, 191842

UniProt: P22223