Cathepsin K anticorps (AA 163-274)
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- Antigène Voir toutes Cathepsin K (CTSK) Anticorps
- Cathepsin K (CTSK)
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Épitope
- AA 163-274
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Cathepsin K est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary)
- Clone
- CTSK-2791
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CTSK Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human liver or breast tissue (IHC).
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- Cathepsin K (CTSK)
- Autre désignation
- CTSK (CTSK Produits)
- Synonymes
- anticorps CTS02, anticorps CTSO, anticorps CTSO1, anticorps CTSO2, anticorps PKND, anticorps PYCD, anticorps AI323530, anticorps MMS10-Q, anticorps Ms10q, anticorps catK, anticorps CTSK, anticorps wu:fa95f03, anticorps wu:fb08b05, anticorps zgc:110367, anticorps cts02, anticorps ctso, anticorps ctso1, anticorps ctso2, anticorps pknd, anticorps pycd, anticorps OC-2, anticorps catk, anticorps cathepsin K, anticorps cathepsin K L homeolog, anticorps Cathepsin K, anticorps CTSK, anticorps Ctsk, anticorps ctsk, anticorps ctsk.L, anticorps catk
- Sujet
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Cathepsin K, Cathepsin O, Cathepsin O1, Cathepsin O2, Cathepsin X, CTS02, Ctsk, CTSO1, CTSO2, PKND, PYCD,Cathepsin K (Marker of Tumor Invasiveness)
Cellular localisation: Cytoplasmic - Poids moléculaire
- 39kDa
- ID gène
- 1513, 632466
- UniProt
- P43235
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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