Desmoglein 3 anticorps (AA 379-491)
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- Antigène Voir toutes Desmoglein 3 (DSG3) Anticorps
- Desmoglein 3 (DSG3)
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Épitope
- AA 379-491
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Desmoglein 3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Coating (Coat)
- Specificité
- Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
- Clone
- DSG3-2796
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product DSG3 Anticorps primaire
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 Reactivité: Humain WB, ELISA, IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivité: Humain IHC Hôte: Souris Monoclonal MSVA-543M unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 Reactivité: Humain ELISA, IF, IHC Hôte: Lapin Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 Reactivité: Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reactivité: Humain WB, ELISA, Coat Hôte: Souris Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reactivité: Humain WB, IF, IHC, FACS, StM Hôte: Souris Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reactivité: Humain WB, IF Hôte: Lapin Monoclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 334-604) antibodyDSG3 Reactivité: Humain WB, IHC, IP, ICC Hôte: Souris Monoclonal C8 unconjugated
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- Indications d'application
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Known_Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- Desmoglein 3 (DSG3)
- Autre désignation
- DSG3 (DSG3 Produits)
- Synonymes
- anticorps DSG3, anticorps CDHF6, anticorps PVA, anticorps bal, anticorps balding, anticorps desmoglein 3, anticorps DSG3, anticorps Dsg3
- Sujet
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130 kDa pemphigus vulgaris antigen (PVA), Balding (Bal), Cadherin family member 6 (CDHF6), Desmoglein-3 (DSG3),Desmoglein-3 (Squamous Cell Marker)
Cellular localisation: Cell Surface - Poids moléculaire
- 130kDa
- ID gène
- 1830, 1925
- UniProt
- P32926
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