EPX anticorps

N° du produit ABIN6937164

Détail du produit anti-EPX anticorps

Antigène: EPX (Eosinophil Peroxidase (EPX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPX est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificité: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human eosinophils from a patient with hypereosinophilic syndrome

Clone: EPO104

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7 cells. Tonsil.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur EPX

Antigène: EPX (Eosinophil Peroxidase (EPX))

Autre désignation: EPX (EPX Produits)

Sujet: Eosinophil peroxidase heavy chain, EPER, EPO, EPP, EPX, EPX PEN, PERE,Eosinophil Peroxidase (EPX)
Cellular localisation: Cytoplasmic, granular

Poids moléculaire: 70kDa (55kDa-Heavy Chain, 15kDa-Light Chain)

ID gène: 8288, 279259

UniProt: P11678