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ETS1 anticorps (AA 137-230)

L’anticorps Souris Monoclonal anti-ETS1 a été validé pour ELISA et Coat. Il convient pour détecter ETS1 dans des échantillons de Humain.
N° du produit ABIN6937200

Aperçu rapide pour ETS1 anticorps (AA 137-230) (ABIN6937200)

Antigène

Voir toutes ETS1 Anticorps
ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Reactivité

  • 124
  • 69
  • 16
  • 8
  • 8
  • 7
  • 6
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 97
  • 29
  • 2
Souris

Clonalité

  • 90
  • 38
Monoclonal

Conjugué

  • 60
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp ETS1 est non-conjugé

Application

  • 94
  • 40
  • 34
  • 33
  • 32
  • 26
  • 26
  • 13
  • 12
  • 7
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Coating (Coat)

Clone

ETS1-1801
  • Épitope

    • 25
    • 22
    • 16
    • 9
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 137-230

    Specificité

    ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant human ETS1 fragment (around aa137-230) (exact sequence is proprietary)

    Isotype

    IgG2b kappa
  • Indications d'application

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2 and HeLa cells. Tonsil, Skin, Pancreas, Kidney and Lymphoma.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

    Autre désignation

    ETS1

    Sujet

    Avian erythroblastosis virus E26 (v ets) oncogene homolog 1, ETS1, EWSR2, p54, v-ets erythroblastosis virus E26 oncogene homolog 1,ETS1 (Marker of Tumor Metastasis)
    Cellular localisation: Nuclear

    Poids moléculaire

    54kDa

    ID gène

    2113, 369438

    UniProt

    P14921
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