FABP5 anticorps

N° du produit ABIN6937209

L’anticorps anti-FABP5 Monoclonal Souris est utilisé pour la détection de FABP5 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour FABP5 anticorps (ABIN6937209)

Antigène: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP5 est non-conjugé

Application: Western Blotting (WB)

Clone: FABP5-3750

Détail du produit anti-FABP5 anticorps

Fonction: FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Antibody

Specificité: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

Réactivité croisée (Details): Human. Others-not tested.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human FABP5 protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application:

Known_Application: Western Blotting (1-2 μg/mL), ,Immunohistology (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur FABP5

Antigène: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Autre désignation: FABP5

Sujet:

FABP5, E-FABP, EFABP, PA-FABP, PAFABP

HeLa, MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.

Poids moléculaire: 15.4kDa

ID gène: 2171, 408061

UniProt: Q01469