FSHB anticorps
Aperçu rapide pour FSHB anticorps (ABIN6937269)
Antigène
Voir toutes FSHB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Full length Purified Human FSH
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Isotype
- IgG1 kappa
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Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL, 30 min RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Anterior Pituitary.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))
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Autre désignation
- FSHB
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Sujet
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Follicle stimulating hormone beta polypeptide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta, FSH-B, FSH-beta, FSHB, FSHbeta,FSH-beta (Follicle Stimulating Hormone-beta)
Cellular localisation: Cytoplasmic, secreted -
Poids moléculaire
- 22kDa
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ID gène
- 2488, 36975
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UniProt
- P01225
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Pathways
- Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
Antigène
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