FTL anticorps (AA 38-165)
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- Antigène Voir toutes FTL Anticorps
- FTL (Ferritin, Light Polypeptide (FTL))
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Épitope
- AA 38-165
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FTL est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
- Specificité
- Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)
- Clone
- FTL-1386
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product FTL Anticorps primaire
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- Indications d'application
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Immunohistology (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Kidney, Cerebellum or Testis.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- FTL (Ferritin, Light Polypeptide (FTL))
- Autre désignation
- FTL (FTL Produits)
- Synonymes
- anticorps NBIA3, anticorps apoferritin, anticorps ferritin, anticorps fhc, anticorps fth, anticorps fth1, anticorps fthl6, anticorps ftn-2, anticorps pig15, anticorps plif, anticorps FT, anticorps Ftl, anticorps Ftl-1, anticorps L-ferritin, anticorps FTL, anticorps Ftl1, anticorps FTL2, anticorps FTD, anticorps ferritin light chain, anticorps ferritin, heavy polypeptide 1 L homeolog, anticorps ferritin light polypeptide 1, anticorps ferritin, light polypeptide, anticorps ferritin light-chain, anticorps ferritin light chain 1, anticorps FTL, anticorps fth1.L, anticorps Ftl1, anticorps CpipJ_CPIJ004069, anticorps Ftl
- Sujet
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Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3,Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker)
Cellular localisation: Cytoplasmic - Poids moléculaire
- 19-25kDa
- ID gène
- 2512, 433670
- UniProt
- P02792
- Pathways
- Transition Metal Ion Homeostasis
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