FUT3 anticorps

N° du produit ABIN6937278

Détail du produit anti-FUT3 anticorps

Antigène: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FUT3 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers.

Réactivité croisée (Details): Human. Guinea Pig.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Mucin isolated from a human ovarian cyst fluid

Clone: 2-25LE-same as LWB01

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Colon.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur FUT3

Antigène: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Autre désignation: FUT3 (FUT3 Produits)

Synonymes: anticorps CD174, anticorps FT3B, anticorps FucT-III, anticorps LE, anticorps Les, anticorps fut356, anticorps FUT3, anticorps ATFUT3, anticorps F1M20.10, anticorps F1M20_10, anticorps fucosyltransferase 3, anticorps fucosyltransferase 3 (Lewis blood group), anticorps fucosyltransferase 3 (Lewis blood group) L homeolog, anticorps fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group), anticorps fucosyltransferase 3, anticorps galactoside 3(4)-L-fucosyltransferase, anticorps FUT3, anticorps fut3.L, anticorps fut3, anticorps LOC697452, anticorps LOC697582

Sujet: Blood group Lewis alpha-4-fucosyltransferase, Fucosyltransferase 3, Fucosyltransferase III, FucT-III, FUT3, Galactoside 3(4)-L-fucosyltransferase, gastric mucin, leB, lewis antigen system, lewis B blood group antigen, Lewis FT, major airway glycoprotein,Blood Group Antigen Lewis B
Cellular localisation: Cytoplasmic

Poids moléculaire: 45kDa

ID gène: 2525, 169238

UniProt: P21217