HHV8 anticorps

N° du produit ABIN6937460

Cet anticorps Rat Monoclonal détecte spécifiquement HHV8 dans IHC, ELISA, Coat, IF et StM. Il présente une réactivité envers Herpes Simplex Virus (HSV).

Aperçu rapide pour HHV8 anticorps (ABIN6937460)

Antigène: HHV8 (Herpes Virus Type 8 (HHV8))

Reactivité: Herpes Simplex Virus (HSV)

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp HHV8 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Immunofluorescence (IF), Staining Methods (StM)

Clone: LN53

Détail du produit anti-HHV8 anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8

Isotype: IgG2c kappa

Information d'application

Indications d'application:

Positive Control: Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue.

Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Buffer: 10 mM PBS without BSA and without Azide.

Agent conservateur: Azide free

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Date de péremption: 24 months

Détails sur HHV8

Antigène: HHV8 (Herpes Virus Type 8 (HHV8))

Autre désignation: Human Herpes Virus 8 (HHV8)

Classe de substances: Virus

Sujet: HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.