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Recombinant IGHG anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement IGHG dans IHC (f). Il présente une réactivité envers Humain.
N° du produit ABIN6937496

Aperçu rapide pour Recombinant IGHG anticorps (ABIN6937496)

Antigène

IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 14
  • 2
Humain

Hôte

  • 8
  • 6
  • 2
Souris

Clonalité

  • 14
  • 2
Monoclonal

Conjugué

  • 15
  • 1
Cet anticorp IGHG est non-conjugé

Application

  • 10
  • 10
  • 7
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone

RIG266
  • Specificité

    Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant full-length human IGHG protein

    Isotype

    IgG1 kappa
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

    Autre désignation

    IGHG

    Sujet

    G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4,IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)
    Cellular localisation: Cytoplasm, Cell Surface and Secreted

    Poids moléculaire

    75kDa

    ID gène

    3500, 3501, 3502

    UniProt

    P01857, P01859, P01860, P01861
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