IGHM anticorps
Aperçu rapide pour IGHM anticorps (ABIN6937515)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) Antibody
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Specificité
- Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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Réactivité croisée (Details)
- Human.
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Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant heavy chain of human IgM
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Isotype
- IgG1, kappa
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Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Raji or hPBL cells. Human tonsil or spleen (IHC).
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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Autre désignation
- IGHM
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Sujet
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AGM1, IGHM, Constant Region of Heavy Chain of IgM, Ig Mu Chain C Region
293T, Raji or hPBL cells. Human tonsil or spleen (IHC).
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Poids moléculaire
- 50-75kDa
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ID gène
- 3507, 510635
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UniProt
- P01871
Antigène
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