IGHM anticorps
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- Antigène Tous les produits IGHM
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IGHM est non-conjugé
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant heavy chain of human IgM
- Clone
- IM260
- Isotype
- IgG1 kappa
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- Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Raji or hPBL cells. Human tonsil or spleen (IHC).
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
- Autre désignation
- IGHM (IGHM Produits)
- Synonymes
- anticorps AI326478, anticorps Igh-6, anticorps Igh-M, anticorps Igh6, anticorps Igm, anticorps muH, anticorps ighm1, anticorps wu:fj14a08, anticorps zgc:101769, anticorps AGM1, anticorps MU, anticorps VH, anticorps immunoglobulin heavy constant mu, anticorps Ighm, anticorps ighm, anticorps IGHM
- Sujet
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AGM1, IGHM, Constant Region of Heavy Chain of IgM, Ig Mu Chain C Region,IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)
Cellular localisation: Cytoplasm, Cell Surface and Secreted - Poids moléculaire
- 50-75kDa
- ID gène
- 3507, 510635
- UniProt
- P01871, P20769
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