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Recombinant IgL anticorps

Reactivité: Humain IHC, IHC (f) Hôte: Lapin Monoclonal rLLC-1738 unconjugated Recombinant Antibody
N° du produit ABIN6937551
  • Antigène Tous les produits IgL
    IgL
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Humain
    Hôte
    • 10
    • 2
    Lapin
    Clonalité
    • 11
    • 1
    Monoclonal
    Conjugué
    • 11
    • 1
    Cet anticorp IgL est non-conjugé
    Application
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Purified human lambda light chain
    Clone
    RLLC-1738
    Isotype
    IgG1 kappa
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human tonsil or spleen tissue (IHC).

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    IgL
    Abstract
    IgL Produits
    Synonymes
    anticorps IGL@, anticorps IGLC6, anticorps igl, anticorps immunoglobulin lambda locus, anticorps IGL, anticorps igl@
    Sujet
    Bence Jones Protein, BJP, IGLC 1/2/3, Mcg Marker, Paraprotein,Lambda Light Chain (B-Cell Marker)
    Cellular localisation: Cell Surface, cytoplasmic and secreted
    Poids moléculaire
    ~22.5kDa
    ID gène
    3535, 3546, 449585
    UniProt
    P01701, P01842
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