IL-10RA anticorps

N° du produit ABIN6937553

Cet anticorps Rat Monoclonal détecte spécifiquement IL-10RA dans FACS, IF et Neut. Il présente une réactivité envers Souris.

Aperçu rapide pour IL-10RA anticorps (ABIN6937553)

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-10RA est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Neutralization (Neut)

Clone: 1B1-3a

Détail du produit anti-IL-10RA anticorps

Specificité: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Aucune reactivité croisée: Humain

Purification: Purified by Protein A/G

Immunogène: Purified recombinant extracellular region of Mouse IL10RA

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: MPBMC's. Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.

Known Application: Neutralization Studies (Order Ab without Azide),Flow Cytometry (0.5-1 μg/million cells in 0.1ml), Immunofluorescence (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Buffer: 10 mM PBS without BSA and without Azide.

Agent conservateur: Azide free

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Date de péremption: 24 months

Détails sur IL-10RA

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Autre désignation: IL-10R1

Poids moléculaire: 90-110kDa

ID gène: 16154

UniProt: Q61727

Pathways: Growth Factor Binding