IL-10RA anticorps
Aperçu rapide pour IL-10RA anticorps (ABIN6937553)
Antigène
Voir toutes IL-10RA (IL10RA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) Antibody
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Specificité
- This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
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Aucune reactivité croisée
- Humain
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Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Purified recombinant extracellular region of Mouse IL10RA
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Isotype
- IgG1, kappa
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Indications d'application
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Positive Control: MPBMC's. Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.
Known Application: Neutralization Studies (Order Ab without Azide),Flow Cytometry (0.5-1 μg/million cells in 0.1ml), Immunofluorescence (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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Autre désignation
- IL-10R1
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Sujet
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CD210 antigen; CDw210a; IBD28; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA IL10RIL-10R subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1
Lung or Liver., lymph node, MPBMC's. Spleen, Placenta, Thymus
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Poids moléculaire
- 90-110kDa
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ID gène
- 16154, 379327
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UniProt
- Q61727
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Pathways
- Growth Factor Binding
Antigène
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