KRT14 anticorps (C-Term)
-
- Antigène Voir toutes KRT14 Anticorps
- KRT14 (Keratin 14 (KRT14))
-
Épitope
- C-Term
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp KRT14 est non-conjugé
-
Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
- Réactivité croisée (Details)
- Human. Mouse. Rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
- Clone
- LL002
- Isotype
- IgG3 kappa
- Top Product
- Discover our top product KRT14 Anticorps primaire
-
-
- Indications d'application
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, A549 or A431 cells. Skin or Squamous cell carcinoma.
- Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
-
- Antigène
- KRT14 (Keratin 14 (KRT14))
- Autre désignation
- KRT14 (KRT14 Produits)
- Synonymes
- anticorps CK14, anticorps EBS3, anticorps EBS4, anticorps K14, anticorps NFJ, anticorps AI626930, anticorps Krt-1.14, anticorps Krt1-14, anticorps Ka14, anticorps ouro2, anticorps keratin 14, anticorps keratin 14, type I L homeolog, anticorps KRT14, anticorps Krt14, anticorps krt14.L
- Sujet
-
CK-14, Dowling Meara, ebs3, ebs4, Epidermolysis Bullosa Simplex, k14, Keratin 14, Keratin Type I Cytoskeletal 14, Koebner, krt14, NFJ,Cytokeratin 14 (KRT14) (Squamous Cell Marker)
Cellular localisation: Cytoplasmic - Poids moléculaire
- 50kDa
- ID gène
- 3861, 6545380
- UniProt
- P02533
-