KRT16 anticorps (C-Term)

N° du produit ABIN6937667

Cet anticorps Souris Monoclonal détecte spécifiquement KRT16 dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour KRT16 anticorps (C-Term) (ABIN6937667)

Antigène: KRT16 (Keratin 16 (KRT16))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT16 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: LL025

Détail du produit anti-KRT16 anticorps

Épitope: C-Term

Specificité: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: A synthetic peptide from the C-terminal of human Cytokeratin 16

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Tonsil, Skin. Bladder or Cervix.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur KRT16

Antigène: KRT16 (Keratin 16 (KRT16))

Autre désignation: KRT16

Sujet: CK16, Cytokeratin-16, Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK), K1CP, Keratin Type I Cytoskeletal 16, Keratin-16, KRT16A,Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker)
Cellular localisation: Cytoplasmic

Poids moléculaire: 48kDa

ID gène: 3868, 655160

UniProt: P08779