Recombinant KRT16 anticorps (C-Term)

N° du produit ABIN6937671

L’anticorps anti-KRT16 Monoclonal Lapin est utilisé pour la détection de KRT16 dans des échantillons de Humain. Il a été validé pour IHC et WB.

Aperçu rapide pour Recombinant KRT16 anticorps (C-Term) (ABIN6937671)

Antigène: KRT16 (Keratin 16 (KRT16))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT16 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: KRT16-2043R

Détail du produit anti-KRT16 anticorps

Épitope: C-Term

Fonction: Recombinant Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker) Antibody

Specificité: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment from the C-terminal of human Cytokeratin 16

Isotype: IgG, kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Tonsil, Skin. Bladder or Cervix.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur KRT16

Antigène: KRT16 (Keratin 16 (KRT16))

Autre désignation: KRT16

Sujet:

CK16, Cytokeratin-16, Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK), K1CP, Keratin Type I Cytoskeletal 16, Keratin-16, KRT16A

HeLa cells. Tonsil, Skin. Bladder or Cervix. Human Sk. Muscle

Poids moléculaire: 48kDa

ID gène: 3868, 655160

UniProt: P08779