Cytokeratin 19 anticorps
Aperçu rapide pour Cytokeratin 19 anticorps (ABIN6937694)
Antigène
Voir toutes Cytokeratin 19 (KRT19) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This Ab reacts with the rod domain of human cytokeratin 19 (CK19), a polypeptide of 40 kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50 % -60 % of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
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Réactivité croisée (Details)
- Human. Mouse.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Human mammary epithelial organoids.
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Isotype
- IgG1 kappa
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Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, HeLa cells, Breast Cancer.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Autre désignation
- KRT19
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Sujet
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K19, k1cs, Keratin 19 Keratin Type i 40kD, krt19,Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker)
Cellular localisation: Cytoplasmic -
Poids moléculaire
- 40kDa
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ID gène
- 3880, 654568
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UniProt
- P08727
Antigène
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