LGALS1/Galectin 1 anticorps (AA 12-108)
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- Antigène Voir toutes LGALS1/Galectin 1 (LGALS1) Anticorps
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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Épitope
- AA 12-108
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LGALS1/Galectin 1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant fragment (around aa12-108) of human Galectin-1 protein (exact sequence is proprietary)
- Clone
- GAL1-1831
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product LGALS1 Anticorps primaire
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- Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: JEG-3, HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Autre désignation
- LGALS1 (LGALS1 Produits)
- Synonymes
- anticorps GAL1, anticorps GBP, anticorps Galectin-1, anticorps LGAS1, anticorps LGALS1, anticorps MGC64502, anticorps GB10026, anticorps AA410090, anticorps Gal-1, anticorps Galbp, anticorps L-14.5, anticorps L14, anticorps Lect14, anticorps galectin-1, anticorps Galaptin, anticorps galectin 1, anticorps galectin-1, anticorps lectin, galactoside-binding, soluble, 1 L homeolog, anticorps protein enabled, anticorps lectin, galactose binding, soluble 1, anticorps LGALS1, anticorps Lgals1, anticorps CC1G_05003, anticorps CC1G_05004, anticorps lgals1.L, anticorps LOC408848
- Sujet
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14 kDa laminin-binding protein, Beta-galactoside-binding lectin L-14-I, Gal-1, GAL1, Galaptin, Galectin-1, HLBP14, HPL, Lactose-binding lectin 1, Lect14, Lectin galactoside-binding soluble 1, LGALS1, MAPK activating protein MP12, S-Lac lectin 1,Galectin-1 / Human Placental Lactogen (hPL)
Cellular localisation: Secreted (extracellular matrix) - Poids moléculaire
- 14kDa
- ID gène
- 3956, 445351
- UniProt
- P09382
- Pathways
- Carbohydrate Homeostasis
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