Recombinant MMP3 anticorps (AA 317-327)

N° du produit ABIN6937884

L’anticorps anti-MMP3 Monoclonal Lapin est utilisé pour la détection de MMP3 dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour Recombinant MMP3 anticorps (AA 317-327) (ABIN6937884)

Antigène: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: MMP3-1994R

Détail du produit anti-MMP3 anticorps

Épitope: AA 317-327

Fonction: Recombinant MMP3 (Marker of Metastasis and Rheumatoid Arthritis) Antibody

Specificité: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified by Protein A.

Immunogène: Recombinant fragment (around aa 317-327) of human MMP3 protein

Isotype: IgG, kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Human prostate or lung tissue. A-431 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MMP3

Antigène: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Autre désignation: MMP3

Sujet:

CHDS6, Matrix metalloproteinase 3, Matrix metalloproteinase-3, MGC126102, MGC126103, MGC126104, MMP 3, MMP-3, MMP3, Proteoglycanase, SL-1, SL1, STMY, STMY1, STR1, Stromelysin 1, Stromelysin-1, Transin 1

Human prostate or lung tissue. A-431 cells.

Poids moléculaire: 57kDa

ID gène: 4314, 375129

UniProt: P08254