Recombinant MUC6 anticorps

N° du produit ABIN6937971

L’anticorps anti-MUC6 Monoclonal Lapin est utilisé pour la détection de MUC6 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant MUC6 anticorps (ABIN6937971)

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC6 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MUC6-1553R

Détail du produit anti-MUC6 anticorps

Fonction: Recombinant MUC6 (Mucin 6 / Gastric Mucin) Antibody

Specificité: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogène: Recombinant full-length human MUC6 protein

Isotype: IgG, kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Human stomach tissue (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MUC6

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Autre désignation: MUC6

Sujet:

Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6

Human stomach tissue (IHC).

Poids moléculaire: 252kDa

ID gène: 4588, 528432

UniProt: Q6W4X9