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Recombinant MUC6 anticorps

MUC6 Reactivité: Humain IHC, IHC (f) Hôte: Lapin Monoclonal MUC6-1553R unconjugated Recombinant Antibody
N° du produit ABIN6937971
  • Antigène Voir toutes MUC6 Anticorps
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 49
    • 4
    • 1
    Humain
    Hôte
    • 29
    • 20
    Lapin
    Clonalité
    • 33
    • 16
    Monoclonal
    Conjugué
    • 22
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MUC6 est non-conjugé
    Application
    • 22
    • 20
    • 19
    • 16
    • 15
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant full-length human MUC6 protein
    Clone
    MUC6-1553R
    Isotype
    IgG
    Top Product
    Discover our top product MUC6 Anticorps primaire
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Human stomach tissue (IHC).

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    Autre désignation
    MUC6 (MUC6 Produits)
    Synonymes
    anticorps gastric, anticorps MUC-6, anticorps mucin-6-like, anticorps mucin 6, oligomeric mucus/gel-forming, anticorps mucin 6, gastric, anticorps LOC100850574, anticorps MUC6, anticorps Muc6
    Sujet
    Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6,MUC6 (Mucin 6 / Gastric Mucin)
    Cellular localisation: Cytoplasmic & Secreted
    Poids moléculaire
    252kDa
    ID gène
    4588, 528432
    UniProt
    Q6W4X9
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