MYH11 anticorps
Aperçu rapide pour MYH11 anticorps (ABIN6937991)
Antigène
Voir toutes MYH11 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Smooth Muscle Myosin Heavy Chain (SM-MHC) Antibody
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Specificité
- Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
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Réactivité croisée (Details)
- Human. Cow. Pig. Dog. Cat. Rabbit. Rat. Guinea Pig. Chicken.
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Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Human uterus extract
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Isotype
- IgG1, kappa
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Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Uterus or normal breast.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
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Autre désignation
- MYH11
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Sujet
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AAT4, Myosin heavy chain 11 (MYH11), Myosin heavy chain 11 smooth muscle, Smooth muscle myosin heavy chain 11, Myosin-11, SM1, SM2, SMHC, SMMHC
Uterus or normal breast.
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Poids moléculaire
- 205kDa (MHC-1) and 200kDa (MHC-2)
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ID gène
- 4629, 460109
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UniProt
- P35749
Antigène
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