Recombinant ODC1 anticorps
Aperçu rapide pour Recombinant ODC1 anticorps (ABIN6938106)
Antigène
Voir toutes ODC1 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
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Réactivité croisée (Details)
- Human. Mouse. Rat.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant full-length human ODC-1 protein
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Isotype
- IgG1 kappa
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Indications d'application
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Known_Application: Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human placenta or prostate carcinoma tissue (IHC).
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- ODC1 (Ornithine Decarboxylase 1 (ODC1))
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Autre désignation
- ODC1
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Sujet
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Ornithine decarboxylase structural 1, RNODC,Ornithine Decarboxylase-1 (ODC-1)
Cellular localisation: Cytoplasmic -
Poids moléculaire
- 53kDa
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ID gène
- 4953, 467701
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UniProt
- P11926
Antigène
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