PAX5 anticorps (AA 235-382)

N° du produit ABIN6938120

Cet anticorps Souris Monoclonal détecte spécifiquement PAX5 dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour PAX5 anticorps (AA 235-382) (ABIN6938120)

Antigène: PAX5 (Paired Box 5 (PAX5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX5 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: PAX5-3735

Détail du produit anti-PAX5 anticorps

Épitope: AA 235-382

Specificité: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 21,000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.

Réactivité croisée (Details): Human. Dog

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: A recombinant fragment (around aa 235-382) of human PAX5 protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Daudi or Ramos cells. Human tonsil, spleen, lymph node or colon carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur PAX5

Antigène: PAX5 (Paired Box 5 (PAX5))

Autre désignation: PAX5

Sujet: B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5,PAX5 / BSAP (Early B-Cell Marker)
Cellular localisation: Nuclear

Poids moléculaire: 42kDa

ID gène: 5079, 654464

UniProt: Q02548