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PAX7 anticorps (AA 301-505)

L’anticorps Souris Monoclonal anti-PAX7 a été validé pour WB, FACS et IF. Il convient pour détecter PAX7 dans des échantillons de Humain.
N° du produit ABIN6938124

Aperçu rapide pour PAX7 anticorps (AA 301-505) (ABIN6938124)

Antigène

Voir toutes PAX7 Anticorps
PAX7 (Paired Box 7 (PAX7))

Reactivité

  • 108
  • 66
  • 51
  • 18
  • 16
  • 8
  • 8
  • 7
  • 7
  • 4
  • 3
  • 3
  • 1
  • 1
Humain

Hôte

  • 72
  • 40
  • 1
  • 1
Souris

Clonalité

  • 64
  • 50
Monoclonal

Conjugué

  • 53
  • 7
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PAX7 est non-conjugé

Application

  • 84
  • 33
  • 32
  • 32
  • 20
  • 15
  • 13
  • 13
  • 13
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone

PAX7-497
  • Épitope

    • 23
    • 16
    • 9
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-505

    Specificité

    The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

    Réactivité croisée (Details)

    Human. Mouse. Rat Chicken. Zebrafish.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)

    Isotype

    IgG1 kappa
  • Indications d'application

    Known_Application: Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, Jurkat, A431, MCF-7, U2OS or NIH/3T3 cells. Rhabdomyosarcoma (RMS).

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    PAX7 (Paired Box 7 (PAX7))

    Autre désignation

    PAX7

    Sujet

    HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2,PAX7 (Rhabdomyosarcoma Marker)
    Cellular localisation: Nuclear

    Poids moléculaire

    57kDa

    ID gène

    5081, 113253

    UniProt

    P23759
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