PDLIM1 anticorps
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- Antigène Voir toutes PDLIM1 Anticorps
- PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PDLIM1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant human full-length PDLIM1 protein
- Clone
- CPTC-PDLIM1-1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product PDLIM1 Anticorps primaire
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- Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 cells and extracts from Jurkat. Human heart, colon or spleen.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))
- Autre désignation
- PDLIM1 (PDLIM1 Produits)
- Synonymes
- anticorps CLIM1, anticorps CLP-36, anticorps CLP36, anticorps hCLIM1, anticorps pdlim1, anticorps MGC76041, anticorps MGC64465, anticorps clim1, anticorps wu:fa19a03, anticorps wu:fy34f10, anticorps zgc:110681, anticorps Clim1, anticorps mClim1, anticorps PDLIM1, anticorps PDZ and LIM domain 1, anticorps PDZ and LIM domain 1 L homeolog, anticorps PDZ and LIM domain 1 (elfin), anticorps PDLIM1, anticorps Pdlim1, anticorps pdlim1, anticorps pdlim1.L
- Sujet
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C terminal LIM domain protein 1, carboxy terminal LIM domain protein 1, CLIM1, CLP36, Elfin, Enigma antibody, Enigma homolog antibody, hCLIM1, PDLIM1, PDZ and LIM domain 1,PDZ and LIM Domain 1
Cellular localisation: Cytoplasm. - Poids moléculaire
- 36kDa
- ID gène
- 9124, 368525
- UniProt
- O00151
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